5) Progeria

Progeria or Hutchinson-Gilford progeria syndrome is a rare genetic disorder that causes rapid aging process. Children born with this genetic abnormality grow physiologically older than their chronological age to the extent that they die in their teens as if they had turned 60 to 70 years and suffer from geriatric pathology. It is not uncommon that stroke and heart attack are the major conditions associated with Progeria. Alopecia, abnormalities in bone and skin are the main symptoms apparent on observation. Cell nucleus mutations to the right causes physical defects to the left. LMNA gene mutation causes the Progeria that affects once in every 8 million births. There is no treatment to this ailment but farnesyltransferase inhibitors fix the damaged cells thus decelerating the pace of aging process.

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